The term Hyphenated techniques ranges from the blend of division ID , hyphenated systems, e.g., GC-MS, LC-MS, LC-FTIR, LC-NMR, CE-MS, and so forth. Hyphenated procedures join chromatographic and ghostly techniques to abuse the benefits of both. partition detachment methods. These system demonstrates specificity and affectability. This strategy is otherwise called twofold half and half. Principle advantage is quick and precise investigation, better reproducibility, decrease of tainting because of its shut framework. A Hyphenated system is mix or coupling of two distinctive systematic strategies with the assistance of two legitimate interface. The point of this coupling is clearly to acquire a data rich location for both ID and measurement contrasted with that with a solitary investigative strategy.